http://www.nytimes.com Good morning.(Don’t get California Today delivered to your inbox? Here’s the sign-up.)On Thursday, Gov. Gavin Newsom declared there would be a “hard close” of state and local beaches in Orange County.“I’m a beach advocate,” Mr. Newsom said. But he added that maintaining access to t
In The Lancet, Yeming Wang and colleagues1 report a randomised trial of remdesivir(200 mg on day 1 followed by 100 mg on days 2–10, in single daily infusions) versusplacebo for adults with severe coronavirus disease 2019 (COVID-19) in ten hospitalsin Wuhan, China. The authors report on 236 patients (140 [59%] men and 96 [41%] women;median age 65 years [IQR 56–71]), with inconclusive findings on the primary outcomeof time to clinical improvement, defined as a two-point improvement on a 6-point ordinalscale,2 a hazard ratio of 1·23 (95% CI 0·87–1·75; favouring remdesivir), and medianobservation times of 21 days (IQR 13–28) in the remdesivir group versus 23 days (15–28)in the placebo group (a non-significant difference).